Manga by author Aro Hiroshi

Shimeru Futaba is a normal high-schooler living a normal life, active in his school's wrestling club and slowly getting closer to his awkward love interest, Misaki. This fails to last as he discovers his family's hereditary genetic defect that becomes active at adolescence. Although it will eventually become controllable, either excitement or stress now makes Futaba switch sex. Hilarity ensues.Translated manga, read left to right.

The title "Yuu & Mi" is a pun on the English phrase "You and Me". Aimu Yuu (remark: his name sounds like "I'm you") is a boy who just moved into the equivalent of a boarding house.Everything is not as it first seems, even the boy. Living in the same room is a ghost (female) named Mi. The series is a combination of love, humour, and a general parody of anime and manga. There are a lot of weird characters in this manga.