Manga by author Sato Zakuri

Kinoshita Mairu has a cute name and she's apologetic for it, because she's ugly. In fact, she's apologetic for her very existence because she's not cute. Classmates call her "Poison Mushroom" behind her back and even her own brother treats her with disdain. However, all of that is about to change with the help of her transvestite mentor/neighbor, Fuwari-chan, and the "school king," Kumada Tenyuu!

From Shinnen: Since childhood, Neiro has been known for being good at fighting, making people fear her and giving her the title of Kansai's strongest woman. Wanting to find romance, she decides to transfer to a high school in Kanto. Instead, what faced her was a specially assembled class of delinquents.

Shinra has a mother who rarely comes home. Everyday, she pinches her pennies just to survive. Rai, a popular guy from her school keeps bothering her, and she's getting sexually harassed by the manager at her part-time job. After finally coming home after 2 months, Shinra's mom promises to stay with her. Rai unexpectedly shows up at Shinra's part-time job and sees her being sexually harassed. He urges her to quit, but she refuses. Shinra comes home only to find out that her mother has disappeared once again